Blu

Chirp is a desktop Twitter client that stands out from all the rest of its kind because of its amazing, dynamic interface.

Its interface lets you have transparencies, follow conversations without missing out on any of whatever you were doing, and write on your twitter account within a really nice-looking environment.

Among its many features you can find: conversation following, unlimited reading of your time line, favorite contacts list and following of direct messages.

Chirp is thus one of the most promising desktop Twitter clients.